Antiprotozoal Activity Against Entamoeba histolytica of Flavonoids Isolated from Lippia graveolens Kunth

Antiprotozoal activity against Entamoeba histolytica of plants used in northeast Mexican traditional medicine. Bioactive compounds from Lippia graveolens and Ruta chalepensis.

Amoebiasis caused by Entamoeba histolytica is associated with high morbidity and mortality is becoming a major public health problem worldwide, especially in developing countries. Because of the side-effects and the resistance that pathogenic protozoa build against the standard antiparasitic drugs, e.g., metronidazole, much recent attention has been paid to plants used in traditional medicine a...

Antiprotozoal activity of flavonoids from Eupatorium arnottianum

María Clavin1, Silvia Cazorla2,3, Renata Spina4, Miguel A. Sosa4, Emilio Malchiodi2, Virginia Martino1, Fernanda Frank2,3,†, Liliana Muschietti1,†,* 1Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Farmacognosia. IQUIMEFA (UBACONICET), Junín 956 2° F (1113), Buenos Aires, Argentina. 2Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Inmunologí...

Activity of Picroliv Isolated from Picrorhiza kurrooa against Thioacetamide and Entamoeba histolytica Induced Liver Damage

Picroliv, an iridoid glycoside mixture, isolated from root and rhizome of Picrorhiza kurrooa known to possess significant hepatoprotective activity. Present study demonstrated the hepatoprotective potential of picroliv against thioacetamide and Entamoeba histolytica induced hepatic damage in rats, mastomys, and gerbils. Significant increase in the serum levels of hapatospecific markers was foun...

Importance of differentiation of Entamoeba histolytica from entamoeba dispar.

Antiprotozoal activity of aporphine alkaloids isolated from Unonopsis buchtienii (Annonaceae).

On a preliminary screening, substantial leishmanicidal activity was observed for the petroleum ether and alkaloidal extracts of the stem bark of Unonopsis buchtienii, the alkaloids and sterols isolated from these were studied. Of the alkaloids, liriodenine exhibited the highest activity against Leishmania major and L donovani (IC100 = 3.12 micrograms/mL). On the other hand, O-methylmoschatoline...